Download<\/a><\/div>Summary of Study Above: <\/p>
The study provided in the document highlights the significant impact of Helicobacter pylori (H. pylori) on iron and vitamin B12 serum levels, indicating that this bacterial infection can lead to deficiencies in these critical nutrients. Here are some key findings from the study:<\/p>
- Iron Levels<\/strong>:<\/li><\/ol>
- The study found that H. pylori infection is associated with lower serum iron levels. This is linked to iron deficiency anemia (IDA), which is prevalent in populations with high H. pylori infection rates.<\/li>\n\n
- The mechanisms suggested include chronic gastritis caused by H. pylori, which can lead to reduced gastric acid secretion, affecting iron absorption.<\/li>\n\n
- After treatment for H. pylori using a combination of omeprazole, amoxicillin, and clarithromycin (OAC), there was a significant improvement in serum iron levels in patients.<\/li><\/ul>
- Vitamin B12 Levels<\/strong>:<\/li><\/ol>
- H. pylori infection also affects vitamin B12 absorption. The study indicates that chronic gastritis induced by H. pylori can reduce the secretion of intrinsic factor, which is necessary for vitamin B12 absorption.<\/li>\n\n
- Several factors contribute to this deficiency, including diminished acid secretion, secretory dysfunction of the intrinsic factor, and decreased secretion of ascorbic acid from the gastric mucosa.<\/li>\n\n
- Following H. pylori eradication treatment, vitamin B12 levels improved significantly, with about 40% of patients showing restored levels.<\/li><\/ul>
- Other Minerals<\/strong>:<\/li><\/ol>